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Thymosin+Alpha-1

Thymosin+Alpha-1

$262.84$328.55

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

Thymosin+Alpha-1+Peptide Thymosin+Alpha-1+peptide,+also+known+as+Thymosin+Alpha,+TA1,+or+T+α+1,+is+a+fragment+of+a+protein+molecule+that+has+been+widely+studied+for+its+potential+implications+with+the+immune+system.+Researchers+have+hypothesized+that+it+contributes+to+the+production+of+T-cells+to+mitigate+and+alleviate+infection+and+bacterial+spread. (1) Thymosin+Alpha-1+is+a+naturally+occurring+polypeptide+that+is+considered+by+researchers+to+potentially+restore+and+enhance+immune+functions. (2) +Thymosin+Alpha-1+is+considered+to+be+one+of+the+polypeptides+found+in+Thymosin+Fraction+5,+which+is+a+crude+extract+of+the+thymus+gland. (3) Since+its+discovery,+a+synthetically+developed+form+of+Thymosin+Alpha-1+has+also+been+studied,+researchers+refer+to+the+peptide+as+Thymalfasin. (2) +Thymalfasin+is+composed+of+28+amino+acids,+similar+to+the+naturally+occurring+Tα+1,+and+is+derived+from+a+longer+polypeptide+precursor+composed+of+113+amino+acids,+known+as+Prothymosin+Alpha. (3) Overview The+main+aim+of+initial+research+into+Thymosin+Alpha-1 (4) +was+to+understand+and+examine+the+immunomodulating+potential+of+the+peptide.+Studies+have+suggested+that+the+peptide+may+increase+the+concentration+of+the+major+histocompatibility+complex+(MHC)+class+I+and+cytokine+production,+which+may+possibly+lead+to+increased+immune+responses.+The+peptide+may+also+enhance+the+activity+of+natural+killer+cells+and+foster+the+expression+of+phenotypic+markers+on+T+cells,+suggesting+a+multi-faceted+role+in+modulating+the+immune+response.+The+researchers+posited+that+the+peptide+may+also+increase+the+expression+of+high-affinity+receptors+for+interleukin-2.+This+could+potentially+lead+to+a+more+vigorous+activation+and+proliferation+of+T+lymphocytes. Researchers+speculate+that+Thymosin+Alpha-1+may+stimulate+possible+action+by+targeting+the+T-helper+cells+and+cytotoxic+T-cell+populations. (3) +Tα+1+may+possibly+induce+differentiation+of+the+T-cells+(thymocytes)+a