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TB-500+(Thymosin+beta+4)

TB-500+(Thymosin+beta+4)

$269.77$337.21

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

TB-500+Peptide TB-500+peptide,+also+known+as+synthetic+Thymosin+Beta+4+or+ Tβ4 +is+the+synthetic+version+of+the+naturally+occurring+protein+Thymosin+beta+4.+The+latter+is+found+naturally+within+the+cells+of+the+thymus+organ+and+encoded+by+the+TMSB4X+gene.+Researchers+have+suggested+TB-500+peptide+hosts+similar+potential+as+Thymosin+beta+4.+These+potential+mechanisms+of+action+may+include+inducing+angiogenesis,+elevating+wound+healing,+or+possibly+elevated+metastatic+potential+of+tumor+cells+and+hair+growth. Besides+being+highly+soluble+in+water+and+light+in+weight,+TB-500+is+a+43+amino+acid-containing+peptide+found+in+abundance+in+the+wound+fluid+comprising+multiple+blood+platelets.+This+peptide+may+exhibit+possible+anti-inflammatory+potential+and+may+support+neurological+healing,+as+well+as+potentially+supporting+healing+processes+in+the+spinal+cord,+heart,+and+epidermis. (1) Overview TB-500+peptide,+also+known+as+thymosin+β(4),+includes+a+distinct+peptide+segment+(17)LKKTETQ(23),+which+acts+as+the+active+site+and+which+researchers+consider+potentially+impactful+in+actin+binding,+cell+migration,+and+wound+healing. (2) +The+amino+acid+sequence+of+TB-500+is: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH. Actins+are+essential+proteins+that+form+a+key+component+of+the+cytoskeleton+within+cells,+serving+not+only+to+maintain+cellular+structure+but+also+to+facilitate+various+cellular+functions,+including+movement.+Actin+is+suggested+to+be+critical+in+supporting+these+cellular+structures+and+processes.+Thymosin+beta-4+and,+thus,+TB-500+are+believed+to+interact+with+actin,+potentially+by+binding+to+globular+actin+(G-actin),+a+precursor+to+filamentous+actin+(F-actin).+This+interaction+is+thought+to+hinder+the+transformation+of+G-actin+into+F-actin,+a+process+known+as+actin+sequestration,+and+is+likely+to+increase+the+av