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Sermorelin+Acetate

Sermorelin+Acetate

$112.89$141.11

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

Sermorelin+Peptide Sermorelin+is+a+29+amino+acid+peptide,+the+shortest+synthetically+developed+peptide+that+may+potentially+induce+biological+activity+at+the+receptors+for+the+growth+hormone-releasing+hormone+(GHRH). (2) +Sermorelin+polypeptide+is+an+analog+of+the+GHRH+factor+consisting+of+GHRH+(1-29+acid)-amide.+Due+to+this+structural+and+functional+mimicry,+Sermorelin+has+been+studied+across+multiple+branches+of+scientific+research+involving+growth+hormone+deficiency+models. (3) It+was+in+the+early+1980s+that+the+action+of+Sermorelin,+classified+as+a+growth+hormone-releasing+fragment+GHRF+(1-29)+amide,+was+first+explored.+Several+research+studies+were+conducted+on+rats+where+exogenous+GHRF+(1-29)+amide+was+introduced+in+conscious+and+anesthetized+rats.+It+was+observed+that+the+presence+of+GHRF+appeared+to+stimulate+the+pituitary+gland+and+promote+growth.+Following+this+theory,+Sermorelin+and+similar+compounds+have+become+the+subject+of+further+research+in+growth+hormone+deficiency+models. (4) Overview Sermorelin+is+suggested+to+be+a+growth+hormone+analog+constituting+the+first+29+amino+acids+out+of+the+usual+44+amino+acids+found+in+growth+hormone-releasing+hormone+(GHRH).+Researchers+posit+that+Sermorelin+binds+with+the+GHRH+receptors+found+on+the+pituitary+gland+and+suggest+further+that+the+synthetic+peptide+may+stimulate+secretion+of+growth+hormone+(hGH).+Thus,+Sermorelin+is+believed+to+maintain+the+fundamental+function+of+GHRH,+possibly+stimulating+the+GHRH+receptors+in+the+pituitary+gland+and+leading+to+sporadic+release+of+growth+hormone+despite+its+reduced+amino+acid+sequence.+This+mechanism+is+thought+to+result+in+increased+levels+of+insulin-like+growth+factor-1+(IGF-1),+primarily+recognized+for+its+role+in+the+anabolic+actions+of+growth+hormone.+The+estimated+half-life+of+Sermorelin+is+around+11+to+12+minutes. A+major+potential+advantage+of+the+peptide+is+that+due+to+its+apparent+GHRH+receptor+specificity,+it+may+not+induce+any+significant+