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Melanotan+2+(MT2)+(10mg)

Melanotan+2+(MT2)+(10mg)

$74.17$92.71

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

Melanotan+2+Peptide Melanotan+2+peptide+is+a+synthetic+compound,+which+is+an+analog+of+the+α-melanocyte-stimulating+hormone. (1) +The+peptide+is+a+cyclic+heptapeptide+that+appears+to+have+a+modified+affinity+towards+the+receptors+that+the+endogenous+hormone+may+interact+with.+In+addition+to+possibly+stimulating+melanogenesis+(the+production+of+melanin+pigment)+in+dermal+cells,+this+peptide+may+have+increased+affinity+towards+other+receptors+that+play+a+role+in+the+regulation+of+appetite+and+various+types+of+arousal. (2) Overview Melanotan+2+likely+serves+as+a+non-selective+agonist+with+the+potential+to+bind+with+four+out+of+the+five+different+subtypes+of+melanocortin+receptors+(MC-R). (3) +Depending+on+the+localization,+the+receptor-Melanotan+2+bond+may+induce+different+actions.+Namely,+the+four+receptors+that+Melanotan+2+may+interact+with+include: The+melanocortin+1+receptor+(MC1R)+may+be+expressed+in+melanocytes,+which+are+cells+found+in+tissues+such+as+dermal+tissues,+hair,+and+possibly+cells+and+tissues+found+in+the+eye. The+melanocortin+3+receptor+(MC3R)+might+be+found+in+a+range+of+tissues,+potentially+including+the+brain+and+the+placenta.+Initial+observations+suggest+that+MC3R+might+be+involved+in+modulating+appetite+under+certain+experimental+conditions. The+melanocortin+4+receptor+(MC4R)+may+be+localized+within+the+central+nervous+system,+perhaps+in+the+hypothalamus.+Some+early+indications+suggest+that+this+receptor+may+impact+neurons+that+are+believed+to+have+some+influence+over+mating+behaviors+and+general+arousal. The+melanocortin+5+receptor+(MC5R)+appears+to+be+distributed+across+multiple+tissues,+although+what+role+it+might+serve+remains+unclear. For+example,+the+potential+interaction+between+Melanotan+2+and+the+MC1Rs+may+lead+to+increased+production+of+eumelanin,+which+causes+darkening+of+the+epidermal+layer’s+pigment. (4) On+the+other+hand,+when+Melanotan+2+binds+with+the+MC4R,+it+may+induce+supraspinal+center