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Melanotan+1+(MT1)+(10mg)

$74.17$92.71

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

Melanotan+1+Peptide Melanotan+1+is+a+synthetic+peptide+similar+to+the+endogenous+alpha-melanocyte+stimulating+hormone+(α-MSH). (1) +Melanotan+1+comprises+13+amino+acids,+the+same+as+α-MSH,+but+differs+by+only+two+amino+acids+from+the+endogenous+peptide+hormone.+This+structural+difference+is+why+researchers+suggest+the+synthetic+peptide+may+exert+a+higher+affinity+towards+the+target+cells+and+boast+a+longer+half-life.+According+to+research,+the+two+notable+modifications+include+the+substitution+of+methionine+and+L-phenylalanine+at+the+fourth+and+seventh+positions+with+norleucine+and+D-phenylalanine,+respectively. (1) Overview Melanotan+1+appears+to+mimic+the+function+of+the+endogenous+α-MSH+and+may+bind+to+the+melanocortin+receptors+to+stimulate+the+production+of+eumelanin,+a+photoprotective+compound.+This+eumelanin+may+protect+tissues+from+any+damage+induced+by+UV+exposure. (1) +Moreover,+eumelanin+production+also+reportedly+contributes+to+increasing+levels+of+pigmentation+in+skin+cells. Chemical+Makeup Molecular+Formula:+ C 78 H 111 N 21 O 19 Molecular+Weight:+ 1646.87+g/mol Other+Known+Titles: +MT1;+afamelanotide Research+and+Clinical+Studies Melanotan+1+and+The+Melanocortin+System Melanotan+1+is+hypothesized+to+exert+its+actions+by+interacting+with+melanocortin+receptors+(MCRs),+which+are+considered+to+be+crucial+signaling+pathways+in+widespread+biological+processes.+It+is+believed+that+five+distinct+melanocortin+receptors+exist,+labeled+melanocortin+1+receptors+(MC1Rs)+through+melanocortin+5+receptors+(MC5Rs),+each+associated+with+specific+potential+roles: (2,3) MC1R:+This+receptor+is+thought+to+reside+in+melanocytes+–+a+kind+of+skin+cell+that+may+influence+skin+and+hair+pigmentation,+potentially+by+promoting+melanin+synthesis. MC2R:+Reportedly+located+in+the+adrenal+cortex,+it+is+suggested+that+this+receptor+may+play+a+role+in+the+production+of+cortisol. MC3R:+Found+in+various+tissues,+including+the+b