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KPV+(10mg)

KPV+(10mg)

$88.69$110.86

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

KPV+Peptide Alpha+melanocyte-stimulating+hormone+(a-MSH)+is+also+classified+as+a+melanotropin.+a-MSH+is+an+endogenous+peptide+hormone,+composed+of+13+amino+acids,+and+considered+to+play+a+role+in+metabolic+function,+as+well+as+other+biological+processes.+Scientists+isolated+a+fragment+of+this+protein+hormone+and+identified+its+potential+biological+action,+naming+it+KPV+peptide.+KPV+comprises+three+amino+acids:+Lysine,+Proline,+and+Valine. (1) +This+peptide+is+a+C-terminal+fragment+of+the+a-MSH+protein+hormone,+which+is+considered+the+primary+amino+acid+sequence+in+the+hormone+responsible+for+its+properties. (2) A+study (2) +was+published+in+1989+explaining+how+the+tripeptide+was+isolated+and+its+biological+potential+determined.+Upon+discovering+that+the+COOH+terminal+peptide+in+the+a-MSH+hormone+is+the+primary+amino+acid+messenger+sequence,+scientists+conducted+preliminary+research+to+determine+if+KPV+might+prevent+an+excessive+increase+in+vasopermeability+and+excessive+swelling+of+blood+vessels.+As+a+part+of+the+study,+scientists+isolated+the+KPV+peptide+and+presented+it+to+experimental+mice+to+determine+its+potential+to+mitigate+swelling+in+their+ears.+After+the+completion+of+the+study,+the+researchers+reported+that+the+isolated+fragment+appeared+to+have+inhibited+the+swelling.+KPV’s+potential+anti-inflammatory+action+may+be+induced+by+inactivating+the+inflammatory+pathways. (3) +It+may+also+possibly+inhibit+the+synthesis+and+release+of+the+pro-inflammatory+cytokine+cells+in+intestinal+and+immune+cells. Chemical+Makeup Molecular+Formula: +C 16 H 30 N 4 O 4 Molecular+Weight: +342.43+g/mol Other+Known+Titles: +MSH+(11-13),+ACTH(11-13),+alpha-MSH(11-13) Research+and+Clinical+Studies KPV+Peptide+and+Intestinal+Protection A+study (4) +was+conducted+on+murine+models+to+determine+the+peptide’s+potential+on+intestinal+inflammation.+The+experiment+was+conducted+on+mice+induced+with+bowel+dysfunction.+These+mice+were+divided+into+two+gr