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Ipamorelin

Ipamorelin

$56.45$70.56

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

Ipamorelin+Peptide Ipamorelin+is+a+synthetic+peptide+that+is+composed+of+five+amino+acids,+otherwise+known+as+a+pentadecapeptide+(Aib-His-D-2-Nal-D-Phe-Lys-NH2),+formally+classified+as+a+Growth+Hormone+Secretagogue+(GHS).+Its+name+is+derived+from+the+intention+of+its+development.+Ipamorelin+peptide+was+designed+to+act+via+ghrelin+receptor+binding.+The+ghrelin+receptors+on+the+pituitary+gland+(the+gland+naturally+involved+with+growth+hormone,+or+hGH+synthesis)+are+also+known+as+Growth+Hormone+Secretagogue+receptors+(GHS-R).+Through+its+implied+action,+Ipamorelin+may+host+the+potential+to+trigger+the+GHS-Rs+on+the+pituitary+gland+and+potentially+stimulate+the+release+of+growth+hormone. (1) Overview Ipamorelin+is+the+first+synthetic+GHS+that+appears+highly+selective+and+may+have+the+potential+to+augment+the+production+of+hGH+without+affecting+other+pituitary+hormones+such+as+prolactin+or+adrenocorticotropic+hormone+(ACTH).+The+potential+increase+in+hGH+might+promote+lipolysis+and+insulin-like+growth+factor-1+(IGF-1)+production+synthesis.+Consequently,+IGF-1+may+become+a+mediator+of+hGH’s+anabolic+actions,+and+thereby+the+peptide+may+act+to+increase+cellular+proliferation+and+bone+and+muscle+anabolism. (1) Chemical+Makeup Molecular+Formula: +C 38 H 49 N 9 O 5 Molecular+Weight: +711.86+g/mol Other+Known+Titles: +NNC+26-0161 Research+and+Clinical+Studies Ipamorelin+Peptide+and+Selective+Agonism Based+on+one+1998+murine+model-based+research+study,+researchers+suggested+that+Ipamorelin+may+release+growth+hormones+from+the+pituitary+cells.+When+Ipamorelin+was+presented+to+swine+and+pentobarbitone+anesthetized+rats,+it+reportedly+exhibited+release+in+growth+hormones.+Upon+further+observation,+the+researchers+hypothesized+that+similar+to+other+growth+hormone+(GH)+stimulating+peptides,+Ipamorelin+may+be+a+growth+receptor+agonist+stimulating+GH+release+through+potential+affinity+in+growth+hormone+receptors.+Moreover,+the+researchers+commented+t