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CJC-1295+With+DAC

CJC-1295+With+DAC

$262.67$328.34

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

CJC-1295+DAC+Peptide CJC-1295+DAC+is+a+peptide+that+researchers+posit+may+function+similarly+to+growth+hormone-releasing+hormone+(GHRH),+potentially+increasing+the+endogenous+production+of+growth+hormone+(GH)+within+the+organism.+The+CJC-1295+DAC+peptide+is+a+synthetic+29+amino+acid+analog+of+GHRH. (1)+ It+is+the+shortest+functional+analog+of+GHRH+that+still+has+the+potential+capacity+to+trigger+GH+release+from+the+somatotroph+cells+in+the+pituitary+gland.+Moreover,+4+of+the+original+29+amino+acids+in+this+fragment+are+substituted+in+CJC-1295+DAC,+to+possibly+improve+the+pharmacokinetics+of+the+peptide+and+prolong+its+half-life. The+DAC+component+is+a+biochemical+complex+that+may+further+increase+the+half-life+of+the+peptide.+This+phenomenon+might+be+ascribed+to+the+alleged+capability+of+the+DAC+to+bind+to+proteins+present+in+plasma.+More+precisely,+the+DAC+component+appears+to+entail+the+attachment+of+a+lysine+derivative,+identified+as+N-epsilon-3-maleimidopropionamide,+to+the+C+terminus+of+CJC-1295+DAC.+Integrating+this+modified+amino+acid+sequence+with+the+DAC+component+might+conceivably+enhance+the+pharmacokinetics+of+CJC-1295+DAC,+extending+its+half-life+to+approximately+8+days.+Simultaneously,+it+appears+to+maintain+a+significant+affinity+for+GHRH+receptors,+similar+to+the+affinity+exhibited+by+CJC-1295+without+DAC. (2) This+does+not+imply+that+CJC+without+DAC+has+no+relevance+or+use+in+present+day+research.+For+example,+has+been+studied+for+its+suggested+synergistic+potential,+as+combining+GHRH+analogs+with+peptides+that+appear+to+activate+the+ghrelin+receptors+in+the+pituitary+gland.+It+is+also+posited+to+result+in+greater+GH-synthesis+response+from+the+somatotroph+cells. (3) Overview CJC-1295+DAC+is+recognized+by+many+names:+CJC-1295,+CJC-1295+with+DAC,+DAC:GRF,+long-acting+GHRH+analog,+and+synthetic+GHRH+analog.+Theoretically,+as+the+peptide+is+considered+a+releasing+factor+for+growth+hormone,+CJC-1295+DAC+has+been+studied+for+its+potentia