Enjoy free shipping on all orders over $250. For items in the "Best Sellers" collection, receive a 25% discount on purchases of 4 or more items, and a 30% discount on purchases of 7 or more items. The website has a transaction limit of $1,000 per order: for higher-value purchases, please contact me directly or split your purchase into multiple smaller orders placed separately on the site.

USD $AccountCart
ARA-290+(10mg)

ARA-290+(10mg)

$112.89$141.11

In stock: 100

Research use only. These products are sold for research purposes only, not for human use. Product comes as lyophilized powder and must be reconstituted before use.

Description

ARA-290+Peptide ARA-290+peptide,+also+known+as+cibinetide+and+helix+B+surface+peptide+(HBSP)+in+scientific+literature,+is+an+11+amino+acid+chain+derived+from+the+beta+domain+of+the+naturally-occurring+protein+erythropoietin+(EPO).+This+part+of+the+EPO+sequence+is+considered+to+assist+in+tissue+regeneration+and+repair+without+exerting+stimulus+on+the+production+of+red+blood+cells. (1) +Scientists+consider+the+primary+function+of+the+EPO+is+to+stimulate+tissues+to+produce+red+blood+cells.+Still,+the+beta+domain+of+the+protein,+and+consequently+ARA-290,+do+not+appear+to+possess+this+property.+Instead,+they+may+possess+certain+potential+regenerative,+anti-inflammatory,+anti-nociceptive,+and+other+lesser-known+properties+of+the+original+naturally+occurring+EPO+protein. Overview Scientific+findings (2) +thus+far+suggest+that+once+a+tissue+undergoes+an+injury,+a+tissue-protective+receptor+(TPR)+pathway+may+be+activated.+This+TPR+receptor+mainly+consists+of+a+beta+receptor+unit+(CD131)+and+a+subunit+from+the+EPO+receptor,+jointly+called+the+innate+repair+receptor.+Researchers+have+suggested+that+the+ARA-290+peptide+molecule+may+bind+to+this+innate+repair+receptor+and+possibly+attenuate+nerve+and+allodynia-led+pain+(nociception). (3) +It+is+also+suggested+that+the+ARA-290+peptide+may+act+primarily+via+this+IRR-mediated+pathway. Chemical+Makeup Molecular+Formula: +C 51 H 54 N 16 O 21 Molecular+Weight: +1257.3+g/mol Other+Known+Titles: +PH-BSP Research+and+Clinical+Studies ARA-290+Peptide+and+Nociception Scientists+consider+that+Transient+Receptor+Potential+(TRP)+channels+may+be+the+primary+nociceptive+stimulating+channels,+including+possible+thermal,+chemical,+and+mechanical+stimuli.+In+the+presence+of+such+a+causative+agent,+one+of+the+TRP+channels,+namely+TRPV1,+may+be+triggered.+Upon+activation,+it+might+induce+the+ejection+of+neuropeptides,+which+then+are+considered+to+generate+action+potential+in+the+nervous+systems.+This+action+potential+is+re